Polymethylsiloxane polyhydrate (Enterosgel) in the complex treatment of children of the first year of life with diseases of the digestive system
https://doi.org/10.21508/1027-4065-2019-64-3-91-96
Abstract
Purpose of the study. Evaluation of the clinical efficacy of polymethylsiloxane polyhydrate (Enterosgel) in the complex treatment of children of the first year of life with diseases of the digestive system.
Patients and methods. The authors carried out a retrospective analysis of the clinical course of diseases of the digestive organs of noninfectious etiology, the study included 38 patients of the first year of life (age 0.40 [0.25; 0.58] years; a continuousstudy of patients), who were treated with Enterosgel in the complex treatment. The comparison group consisted of 12 children (age 0.42 [0.25; 0.60] years) with diseases of the digestive organs, who did notreceive Enterosgel in complex treatment. The authors carried out a comparative assessment of the symptoms of intoxication, the nature of the stool, indicators of clinical blood tests and length of stay in the hospital.
Results. The patients treated with Enterosgel demonstrated faster relief of intoxication symptoms and stool normalization; the length of hospital stay decreased 2 times, negative changes in blood tests and side effects of the drug were not observed.
Conclusion. Complex treatment with Enterosgel of the diseases of the digestive organs in children of the first year of life is accompanied by more rapid relief of pathological symptoms and it reduces stay in the hospital, it is not accompanied by side effects, allowing us to recommend Enterosgel for the complex treatment of children of the first year of life.
Supporting agencies: Financial support. The work was initiated and financially supported by TNK SILMA LLC (Russia)
About the Authors
A. I. Khavkin
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
G. V. Volynets
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
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Review
For citations:
Khavkin A.I., Volynets G.V. Polymethylsiloxane polyhydrate (Enterosgel) in the complex treatment of children of the first year of life with diseases of the digestive system. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2019;64(3):91-96. (In Russ.) https://doi.org/10.21508/1027-4065-2019-64-3-91-96
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